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Assay Detail

CHEMBL2208693

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Anti-platelet activity in human platelet-rich plasma assessed as inhibition of collagen-induced platelet aggregation
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Tissue Plasma
Cell Type Platelet
Confidence 1 — Organism
Curated By Autocuration

Target

Platelet (CHEMBL4296519)
Type CELL-LINE

Publication

Synopsis of some recent tactical application of bioisosteres in drug design.
Meanwell NA.
J Med Chem (2011) 54 : 2529 -2591
PubMed 21413808 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 3 7.04 7.57

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL125569 1 7.57
CHEMBL419780 1 6.80
CHEMBL326075 1 6.75

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL125569 EC50 = 27.0 nM 7.57
CHEMBL419780 EC50 = 160.0 nM 6.80
CHEMBL326075 EC50 = 180.0 nM 6.75