Assay Detail
Binding
CHEMBL2208697
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Binding affinity to Bcl2 by fluorescent polarization assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synopsis of some recent tactical application of bioisosteres in drug design.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.03 | 7.03 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL371861 | — | — | 1 | 7.03 |
| CHEMBL449132 | — | — | 1 | - |
| CHEMBL106708 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL371861 | — | IC50 | = | 93.0 | nM | 7.03 |
| CHEMBL449132 | — | IC50 | = | 4300000.0 | nM | - |
| CHEMBL106708 | — | IC50 | = | 300000.0 | nM | - |