Assay Detail
Functional
CHEMBL2208700
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonist activity at angiotensin 2 receptor
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synopsis of some recent tactical application of bioisosteres in drug design.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 7.30 | 8.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL165354 | — | — | 1 | 8.70 |
| CHEMBL191 | LOSARTAN | 4.0 | 1 | 7.72 |
| CHEMBL2205685 | — | — | 1 | 7.60 |
| CHEMBL165572 | — | — | 1 | 7.00 |
| CHEMBL86067 | — | — | 1 | 6.85 |
| CHEMBL274447 | — | — | 1 | 6.70 |
| CHEMBL166143 | — | — | 1 | 6.56 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL165354 | — | IC50 | = | 2.0 | nM | 8.70 |
| CHEMBL191 | LOSARTAN | IC50 | = | 19.0 | nM | 7.72 |
| CHEMBL2205685 | — | IC50 | = | 25.0 | nM | 7.60 |
| CHEMBL165572 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL86067 | — | IC50 | = | 140.0 | nM | 6.85 |
| CHEMBL274447 | — | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL166143 | — | IC50 | = | 275.0 | nM | 6.56 |