Assay Detail
Binding
CHEMBL2208702
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of mGluR1a receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synopsis of some recent tactical application of bioisosteres in drug design.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.38 | 4.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL43412 | — | — | 1 | 4.60 |
| CHEMBL2204334 | — | — | 1 | 4.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL43412 | — | IC50 | = | 25000.0 | nM | 4.60 |
| CHEMBL2204334 | — | IC50 | = | 68900.0 | nM | 4.16 |