Assay Detail
Binding
CHEMBL2208733
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of EP3 receptor
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Prostaglandin E2 receptor EP3 subtype (CHEMBL3710) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Synopsis of some recent tactical application of bioisosteres in drug design.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 8.07 | 8.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL220802 | — | — | 1 | 8.96 |
| CHEMBL2204339 | — | — | 1 | 8.68 |
| CHEMBL2204337 | — | — | 1 | 8.17 |
| CHEMBL2204340 | — | — | 1 | 8.00 |
| CHEMBL2204338 | — | — | 1 | 7.77 |
| CHEMBL2204336 | — | — | 1 | 6.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL220802 | — | Ki | = | 1.1 | nM | 8.96 |
| CHEMBL2204339 | — | Ki | = | 2.1 | nM | 8.68 |
| CHEMBL2204337 | — | Ki | = | 6.7 | nM | 8.17 |
| CHEMBL2204340 | — | Ki | = | 9.9 | nM | 8.00 |
| CHEMBL2204338 | — | Ki | = | 17.0 | nM | 7.77 |
| CHEMBL2204336 | — | Ki | = | 153.0 | nM | 6.82 |