Assay Detail
Binding
CHEMBL2209966
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of hemagglutininin in Influenza A virus (A/X-31(H3N2)) infected in chicken red blood cells assessed as inhibition of hemolysis preincubated for 1 hr prior to addition of red blood cells measured at pH 5.0 by spectrophotometric analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Influenza A virus (A/X-31(H3N2)) |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Hemagglutinin (CHEMBL4918) ↗| Type | SINGLE PROTEIN |
| Organism | Influenza A virus (strain A/X-31 H3N2) |
Publication
Microwave assisted synthesis and anti-influenza virus activity of 1-adamantyl substituted N-(1-thia-4-azaspiro[4.5]decan-4-yl)carboxamide derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.51 | 5.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2207987 | — | — | 1 | 5.58 |
| CHEMBL2207978 | — | — | 1 | 5.43 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2207987 | — | IC50 | = | 2600.0 | nM | 5.58 |
| CHEMBL2207978 | — | IC50 | = | 3700.0 | nM | 5.43 |