Assay Detail
Functional
CHEMBL2211013
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Antitumor activity against human LoVo cells assessed as inhibition of cell proliferation after 2 days by MTT assay
5
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | LoVo |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis, characterization and biological evaluation of ureidofibrate-like derivatives endowed with peroxisome proliferator-activated receptor activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.56 | 4.77 |
| Inhibition | 2 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL477119 | — | — | 2 | 4.77 |
| CHEMBL479207 | — | — | 2 | 4.72 |
| CHEMBL408 | TROGLITAZONE | 4.0 | 1 | 4.19 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL477119 | — | IC50 | = | 17000.0 | nM | 4.77 |
| CHEMBL479207 | — | IC50 | = | 19000.0 | nM | 4.72 |
| CHEMBL408 | TROGLITAZONE | IC50 | = | 65000.0 | nM | 4.19 |
| CHEMBL477119 | — | Inhibition | - | % | - | |
| CHEMBL479207 | — | Inhibition | - | % | - |