Assay Detail

CHEMBL2212304

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Functional

Cytotoxicity against human PC6 cells by MTT assay

ChEMBL ↗

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Target

PC-6 (CHEMBL614235) ↗

Open DB target context

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PC-6 (CHEMBL614235) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target PC-6

CHEMBL614235

Anchored from Assay target.

Protein identity PC-6

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	PC-6
Confidence	1 — Organism
Curated By	Autocuration

Target

PC-6 (CHEMBL614235) ↗

Type	CELL-LINE
Organism	Homo sapiens

Publication

PPARγ agonist from Chromolaena odorata.

Zhang ML, Irwin D, Li XN, Sauriol F, Shi XW, Wang YF, Huo CH, Li LG, Gu YC, Shi QW.
J Nat Prod (2012) 75 : 2076 -2081
PubMed 23186307 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	4.28	4.28

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL2208191	—	—	1	4.28

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL2208191	—	IC50	=	52210.0	nM	4.28