Assay Detail
Binding
CHEMBL2212817
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of thiazine red R from amyloid beta (1 to 40) aggregate after 30 mins by fluorimetric analysis
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
2-Styrylindolium based fluorescent probes visualize neurofibrillary tangles in Alzheimer's disease.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 6.71 | 8.86 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2203332 | — | — | 1 | 8.86 |
| CHEMBL2181036 | — | — | 1 | 6.85 |
| CHEMBL207649 | — | — | 1 | 5.83 |
| CHEMBL93124 | PITTSBURGH COMPOUND B UNLABELLED | 2.0 | 1 | 5.29 |
| CHEMBL2207756 | — | — | 1 | - |
| CHEMBL2069534 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2203332 | — | IC50 | = | 1.37 | nM | 8.86 |
| CHEMBL2181036 | — | IC50 | = | 140.0 | nM | 6.85 |
| CHEMBL207649 | — | IC50 | = | 1467.0 | nM | 5.83 |
| CHEMBL93124 | PITTSBURGH COMPOUND B UNLABELLED | IC50 | = | 5190.0 | nM | 5.29 |
| CHEMBL2207756 | — | IC50 | - | — | - | |
| CHEMBL2069534 | — | IC50 | > | 10000.0 | nM | - |