Assay Detail
Binding
CHEMBL2213354
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Inhibition of human aromatase activity after 30 mins by fluorescence analysis
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Optimization of thiazole analogues of resveratrol for induction of NAD(P)H:quinone reductase 1 (QR1).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.62 | 6.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL9352 | NARINGENIN | — | 1 | 6.64 |
| CHEMBL165 | RESVERATROL | 3.0 | 1 | 4.59 |
| CHEMBL2208141 | — | — | 1 | - |
| CHEMBL2208140 | — | — | 1 | - |
| CHEMBL2208131 | — | — | 1 | - |
| CHEMBL1939530 | — | — | 1 | - |
| CHEMBL264401 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL9352 | NARINGENIN | IC50 | = | 230.0 | nM | 6.64 |
| CHEMBL165 | RESVERATROL | IC50 | = | 25400.0 | nM | 4.59 |
| CHEMBL2208141 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL2208140 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL2208131 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL1939530 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL264401 | — | IC50 | > | 32700.0 | nM | - |