Assay Detail
Functional
CHEMBL2215931
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Antiviral activity against Influenza B virus B/Sichuan/379/99 infected in MDCK cells assessed as protection against virus-induced cytopathic effect after 48 to 72 hrs by CellTiter 96 aqueous assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Influenza B virus |
| Cell Type | MDCK |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Development of oseltamivir phosphonate congeners as anti-influenza agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 5.77 | 6.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2206458 | TAMIPHOSPHOR MONOETHYL ESTER | — | 1 | 6.16 |
| CHEMBL2206456 | TAMIPHOSPHOR | — | 1 | 5.37 |
| CHEMBL2206932 | TAMIPHOSPHOR MONOETHYL ESTER | — | 1 | - |
| CHEMBL2206459 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2206458 | TAMIPHOSPHOR MONOETHYL ESTER | EC50 | = | 695.0 | nM | 6.16 |
| CHEMBL2206456 | TAMIPHOSPHOR | EC50 | = | 4250.0 | nM | 5.37 |
| CHEMBL2206932 | TAMIPHOSPHOR MONOETHYL ESTER | EC50 | > | 10000.0 | nM | - |
| CHEMBL2206459 | — | EC50 | > | 10000.0 | nM | - |