Assay Detail
Functional
CHEMBL2216650
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Cytotoxicity against human HeLa cells after 72 hrs by alamar blue assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HeLa |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cytotoxic cyclic depsipeptides from the Australian marine sponge Neamphius huxleyi.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.96 | 7.44 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL501867 | VINCRISTINE SULFATE | 4.0 | 1 | 7.44 |
| CHEMBL2208229 | — | — | 1 | 6.96 |
| CHEMBL2208228 | — | — | 1 | 6.77 |
| CHEMBL2208227 | — | — | 1 | 6.68 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL501867 | VINCRISTINE SULFATE | IC50 | = | 36.0 | nM | 7.44 |
| CHEMBL2208229 | — | IC50 | = | 110.0 | nM | 6.96 |
| CHEMBL2208228 | — | IC50 | = | 170.0 | nM | 6.77 |
| CHEMBL2208227 | — | IC50 | = | 210.0 | nM | 6.68 |