Assay Detail
Binding
CHEMBL2217022
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Inhibition of carnitine palmitoyltransferase in 18 hr fasted rat liver homogenates
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Tissue | Liver |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Carnitine palmitoyltransferase (CPT) modulators: a medicinal chemistry perspective on 35 years of research.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.17 | 5.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1231507 | PALMITOYLAMINOCARNITINE | — | 1 | 5.89 |
| CHEMBL114113 | — | — | 1 | 4.44 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1231507 | PALMITOYLAMINOCARNITINE | IC50 | = | 1300.0 | nM | 5.89 |
| CHEMBL114113 | — | IC50 | = | 36000.0 | nM | 4.44 |