Assay Detail
Binding
CHEMBL2217060
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Competitive inhibition of CPT2 in liver mitochondria using carnitine
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Tissue | Liver |
| Subcellular | Mitochondria |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Carnitine O-palmitoyltransferase 2, mitochondrial (CHEMBL3238) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Carnitine palmitoyltransferase (CPT) modulators: a medicinal chemistry perspective on 35 years of research.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 5.38 | 5.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL48257 | HEMIACYLCARNITINIUM | — | 1 | 5.38 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL48257 | HEMIACYLCARNITINIUM | Ki | = | 4200.0 | nM | 5.38 |