Assay Detail
Functional
CHEMBL2317870
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against Vesicular stomatitis virus infected in human HEL cells assessed as reduction of viral replication
4
Total Activities
4
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Vesicular stomatitis virus |
| Cell Type | HEL |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Vesicular stomatitis virus (CHEMBL613739) ↗| Type | ORGANISM |
| Organism | Vesicular stomatitis virus |
Publication
C-3 halo and 3-methyl substituted 5'-nor-3-deazaaristeromycins: synthesis and antiviral properties.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 5.25 | 5.40 |
| Activity | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2312735 | — | — | 1 | 5.40 |
| CHEMBL2312734 | — | — | 1 | 5.10 |
| CHEMBL2312733 | — | — | 1 | - |
| CHEMBL2312736 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2312735 | — | EC50 | = | 4000.0 | nM | 5.40 |
| CHEMBL2312734 | — | EC50 | = | 8000.0 | nM | 5.10 |
| CHEMBL2312733 | — | Activity | - | — | - | |
| CHEMBL2312736 | — | EC50 | > | 200000.0 | nM | - |