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Assay Detail

CHEMBL2318150

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human Daudi cells assessed as growth inhibition after 3 to 5 days by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type Daudi
Confidence 1 — Organism
Curated By Autocuration

Target

Daudi (CHEMBL614281)
Type CELL-LINE
Organism Homo sapiens

Publication

Pharmacophore identification of c-Myc inhibitor 10074-G5.
Yap JL, Wang H, Hu A, Chauhan J, Jung KY, Gharavi RB, Prochownik EV, Fletcher S.
Bioorg Med Chem Lett (2013) 23 : 370 -374
PubMed 23177256 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 4.63 5.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2312756 1 5.00
CHEMBL1336889 1 4.25

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2312756 IC50 = 10000.0 nM 5.00
CHEMBL1336889 IC50 = 56000.0 nM 4.25