Assay Detail
Binding
CHEMBL2318592
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to human FIH catalytic domain Mn2 expressed in Escherichia coli by NMR spectroscopic analysis
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Reporter ligand NMR screening method for 2-oxoglutarate oxygenase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 4.96 | 5.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL90852 | N-OXALYLGLYCINE | — | 1 | 5.40 |
| CHEMBL1230640 | — | — | 1 | 4.52 |
| CHEMBL426560 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL90852 | N-OXALYLGLYCINE | Kd | = | 4000.0 | nM | 5.40 |
| CHEMBL1230640 | — | Kd | = | 30000.0 | nM | 4.52 |
| CHEMBL426560 | — | Kd | = | 140000.0 | nM | - |