Assay Detail
Binding
CHEMBL2319301
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to galectin-3 (unknown origin) by fluorescence polarization assay
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Tuning the preference of thiodigalactoside- and lactosamine-based ligands to galectin-3 over galectin-1.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 9 | 5.80 | 7.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2313626 | — | — | 1 | 7.66 |
| CHEMBL2313627 | — | — | 1 | 7.36 |
| CHEMBL2313338 | — | — | 1 | 6.44 |
| CHEMBL2313337 | — | — | 1 | 5.92 |
| CHEMBL2313335 | — | — | 1 | 5.66 |
| CHEMBL2313334 | — | — | 1 | 5.55 |
| CHEMBL2313336 | — | — | 1 | 5.09 |
| CHEMBL52011 | THIODIGALACTOSIDE | — | 1 | 4.37 |
| CHEMBL502001 | — | — | 1 | 4.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2313626 | — | Kd | = | 22.0 | nM | 7.66 |
| CHEMBL2313627 | — | Kd | = | 44.0 | nM | 7.36 |
| CHEMBL2313338 | — | Kd | = | 360.0 | nM | 6.44 |
| CHEMBL2313337 | — | Kd | = | 1200.0 | nM | 5.92 |
| CHEMBL2313335 | — | Kd | = | 2200.0 | nM | 5.66 |
| CHEMBL2313334 | — | Kd | = | 2800.0 | nM | 5.55 |
| CHEMBL2313336 | — | Kd | = | 8100.0 | nM | 5.09 |
| CHEMBL52011 | THIODIGALACTOSIDE | Kd | = | 43000.0 | nM | 4.37 |
| CHEMBL502001 | — | Kd | = | 69000.0 | nM | 4.16 |