Assay Detail
Binding
CHEMBL2319306
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at GHSR (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Growth hormone secretagogue receptor type 1 (CHEMBL4616) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Systematic exploration of dual-acting modulators from a combined medicinal chemistry and biology perspective.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 7.87 | 9.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL13817 | IBUTAMOREN | 2.0 | 1 | 9.70 |
| CHEMBL473921 | — | — | 1 | 7.00 |
| CHEMBL501315 | — | — | 1 | 6.90 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL13817 | IBUTAMOREN | EC50 | = | 0.1995 | nM | 9.70 |
| CHEMBL473921 | — | EC50 | = | 100.0 | nM | 7.00 |
| CHEMBL501315 | — | EC50 | = | 125.89 | nM | 6.90 |