Assay Detail
Functional
CHEMBL2320751
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Antiproliferative activity against human PC3 cells after 72 hrs after ATPlite kit assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | PC-3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Enhanced bioactivity of silybin B methylation products.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.67 | 5.09 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2313579 | — | — | 1 | 5.09 |
| CHEMBL2313580 | — | — | 1 | 4.84 |
| CHEMBL2313578 | — | — | 1 | 4.77 |
| CHEMBL2313581 | — | — | 1 | 4.66 |
| CHEMBL2313577 | — | — | 1 | 4.44 |
| CHEMBL592675 | SILYBIN B | — | 1 | 4.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2313579 | — | IC50 | = | 8100.0 | nM | 5.09 |
| CHEMBL2313580 | — | IC50 | = | 14400.0 | nM | 4.84 |
| CHEMBL2313578 | — | IC50 | = | 16900.0 | nM | 4.77 |
| CHEMBL2313581 | — | IC50 | = | 21900.0 | nM | 4.66 |
| CHEMBL2313577 | — | IC50 | = | 36300.0 | nM | 4.44 |
| CHEMBL592675 | SILYBIN B | IC50 | = | 60500.0 | nM | 4.22 |