Assay Detail
Binding
CHEMBL2327150
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of CDK4 (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of a highly potent, orally active mitosis/angiogenesis inhibitor r1530 for the treatment of solid tumors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.52 | 6.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2322701 | — | — | 1 | 6.52 |
| CHEMBL1980391 | RG-1530 | 1.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2322701 | — | IC50 | = | 303.0 | nM | 6.52 |
| CHEMBL1980391 | RG-1530 | IC50 | > | 10000.0 | nM | - |