Assay Detail
Binding
CHEMBL2327249
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Inhibition of caspase-6 (unknown origin)
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Irreversible inhibitors of cysteine proteases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.11 | 6.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2324339 | — | — | 1 | 6.22 |
| CHEMBL2324340 | — | — | 1 | 4.00 |
| CHEMBL2324341 | — | — | 1 | - |
| CHEMBL2323967 | — | — | 1 | - |
| CHEMBL2323966 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2324339 | — | IC50 | = | 600.0 | nM | 6.22 |
| CHEMBL2324340 | — | IC50 | = | 100000.0 | nM | 4.00 |
| CHEMBL2324341 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL2323967 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL2323966 | — | IC50 | > | 100000.0 | nM | - |