Assay Detail
Binding
CHEMBL2327432
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of TREK-1 (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Potassium channel subfamily K member 2 (CHEMBL2321615) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Ion channels as therapeutic targets: a drug discovery perspective.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.40 | 6.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1491 | AMLODIPINE | 4.0 | 1 | 6.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1491 | AMLODIPINE | IC50 | = | 400.0 | nM | 6.40 |