Assay Detail
Binding
CHEMBL2327591
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of wild type Human immunodeficiency virus 1 NL4-3 envelope glycoprotein gp160-mediated cell-cell fusion between virus-infected monkey COS cells to human TZM-bl cells after 24 hrs by luciferase reporter gene assay
3
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Human immunodeficiency virus 1 |
| Cell Type | COS |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
New betulinic acid derivatives for bevirimat-resistant human immunodeficiency virus type-1.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Inhibition | 2 | - | - |
| IC50 | 1 | 7.38 | 7.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL508943 | — | — | 1 | 7.38 |
| CHEMBL2324156 | — | — | 1 | - |
| CHEMBL404519 | BEVIRIMAT | 2.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL508943 | — | IC50 | = | 42.0 | nM | 7.38 |
| CHEMBL2324156 | — | Inhibition | - | % | - | |
| CHEMBL404519 | BEVIRIMAT | Inhibition | - | % | - |