Assay Detail
Binding
CHEMBL2328933
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human UAE-catalyzed E1-E2 transthiolation reaction expressed in Sf9 insect cells after 90 mins by TR-FRET assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | Sf9 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Exploring a new frontier in cancer treatment: targeting the ubiquitin and ubiquitin-like activating enzymes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.85 | 8.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2017005 | — | — | 1 | 8.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2017005 | — | IC50 | = | 1.4 | nM | 8.85 |