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Assay Detail

CHEMBL2329702

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Binding
Binding affinity to Clostridium botulinum neurotoxin A light chain at 390 uM by isothermal titration assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Clostridium botulinum
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Botulinum neurotoxin type A (CHEMBL5192)
Type SINGLE PROTEIN
Organism Clostridium botulinum

Publication

Paclitaxel is an inhibitor and its boron dipyrromethene derivative is a fluorescent recognition agent for botulinum neurotoxin subtype A.
Dadgar S, Ramjan Z, Floriano WB.
J Med Chem (2013) 56 : 2791 -2803
PubMed 23484537 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 5.34 5.34

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL289577 1 5.34

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL289577 Kd = 4600.0 nM 5.34