Assay Detail
Binding
CHEMBL2338993
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Inhibition of vitronectin binding to Integrin alphaVbeta5 receptor (unknown origin) by competitive ELISA
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Biselectivity of isoDGR peptides for fibronectin binding integrin subtypes α5β1 and αvβ6: conformational control through flanking amino acids.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 7.32 | 8.12 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL429876 | CILENGITIDE | 3.0 | 1 | 8.12 |
| CHEMBL2332367 | — | — | 1 | 6.51 |
| CHEMBL2332368 | — | — | 1 | - |
| CHEMBL916 | TIROFIBAN | 4.0 | 1 | - |
| CHEMBL2332369 | — | — | 1 | - |
| CHEMBL2332827 | — | — | 1 | - |
| CHEMBL2332833 | — | — | 1 | - |
| CHEMBL2332834 | — | — | 1 | - |
| CHEMBL2332839 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL429876 | CILENGITIDE | IC50 | = | 7.6 | nM | 8.12 |
| CHEMBL2332367 | — | IC50 | = | 310.0 | nM | 6.51 |
| CHEMBL2332368 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL916 | TIROFIBAN | IC50 | - | — | - | |
| CHEMBL2332369 | — | IC50 | - | — | - | |
| CHEMBL2332827 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL2332833 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL2332834 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL2332839 | — | IC50 | > | 10000.0 | nM | - |