Assay Detail
Binding
CHEMBL2339846
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Inhibition of Plasmodium falciparum recombinant Falcipain-2 using Z-LR-AMC as substrate after 30 mins by microplate reader analysis
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Plasmodium falciparum |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis and insight into the structure-activity relationships of chalcones as antimalarial agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.16 | 5.34 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2335727 | — | — | 1 | 5.34 |
| CHEMBL2336170 | — | — | 1 | 5.26 |
| CHEMBL2336169 | — | — | 1 | 4.87 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2335727 | — | IC50 | = | 4600.0 | nM | 5.34 |
| CHEMBL2336170 | — | IC50 | = | 5500.0 | nM | 5.26 |
| CHEMBL2336169 | — | IC50 | = | 13500.0 | nM | 4.87 |