Assay Detail
Functional
CHEMBL2341715
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiplasmodial activity against chloroquine-resistant Plasmodium falciparum NF54 after 48 hrs by [3H]-hypoxanthine incorporation assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Antibacterial and antiplasmodial constituents of Beilschmiedia cryptocaryoides.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.61 | 8.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL76 | CHLOROQUINE | 4.0 | 1 | 8.70 |
| CHEMBL2334426 | CRYPTOBEILIC ACID B | — | 1 | 5.27 |
| CHEMBL1821986 | TSANGIBEILIN B | — | 1 | 5.09 |
| CHEMBL2334428 | CRYPTOBEILIC ACID D | — | 1 | 4.97 |
| CHEMBL2334427 | CRYPTOBEILIC ACID C | — | 1 | 4.85 |
| CHEMBL2334425 | CRYPTOBEILIC ACID A | — | 1 | 4.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL76 | CHLOROQUINE | IC50 | = | 2.0 | nM | 8.70 |
| CHEMBL2334426 | CRYPTOBEILIC ACID B | IC50 | = | 5350.0 | nM | 5.27 |
| CHEMBL1821986 | TSANGIBEILIN B | IC50 | = | 8200.0 | nM | 5.09 |
| CHEMBL2334428 | CRYPTOBEILIC ACID D | IC50 | = | 10800.0 | nM | 4.97 |
| CHEMBL2334427 | CRYPTOBEILIC ACID C | IC50 | = | 14000.0 | nM | 4.85 |
| CHEMBL2334425 | CRYPTOBEILIC ACID A | IC50 | = | 17700.0 | nM | 4.75 |