Assay Detail
Binding
CHEMBL2341921
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to human PPARdelta (unknown origin) by competitive TR-FRET assay
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Peroxisome proliferator-activated receptor delta (CHEMBL3979) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Structural characterization of amorfrutins bound to the peroxisome proliferator-activated receptor γ.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 9 | 6.12 | 9.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL38508 | — | — | 1 | 9.40 |
| CHEMBL2337127 | — | — | 1 | 5.75 |
| CHEMBL2337126 | — | — | 1 | 4.77 |
| CHEMBL491820 | AMORFRUTIN A | — | 1 | 4.57 |
| CHEMBL21241 | GW7647 | — | 1 | - |
| CHEMBL1204498 | — | — | 1 | - |
| CHEMBL2337128 | — | — | 1 | - |
| CHEMBL370152 | — | — | 1 | - |
| CHEMBL121 | ROSIGLITAZONE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL38508 | — | Kd | = | 0.4 | nM | 9.40 |
| CHEMBL2337127 | — | Kd | = | 1800.0 | nM | 5.75 |
| CHEMBL2337126 | — | Kd | = | 17000.0 | nM | 4.77 |
| CHEMBL491820 | AMORFRUTIN A | Kd | = | 27000.0 | nM | 4.57 |
| CHEMBL21241 | GW7647 | Kd | - | — | - | |
| CHEMBL1204498 | — | Kd | - | — | - | |
| CHEMBL2337128 | — | Kd | - | — | - | |
| CHEMBL370152 | — | Kd | - | — | - | |
| CHEMBL121 | ROSIGLITAZONE | Kd | - | — | - |