Assay Detail
Binding
CHEMBL2342282
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to TSG4 primer DNA (unknown origin) assessed as inhibition of telomerase-mediated extension of primer after 3 hrs by fluorescence-based TRAP assay
4
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Not specified |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Telomere shortening and cell senescence induced by perylene derivatives in A549 human lung cancer cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Inhibition | 2 | - | - |
| IC50 | 2 | 5.98 | 6.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2181585 | — | — | 2 | 6.10 |
| CHEMBL359594 | — | — | 2 | 5.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2181585 | — | IC50 | = | 800.0 | nM | 6.10 |
| CHEMBL359594 | — | IC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL359594 | — | Inhibition | - | % | - | |
| CHEMBL2181585 | — | Inhibition | - | % | - |