Assay Detail
Functional
CHEMBL2342808
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Antimalarial activity against chloroquine-resistant Plasmodium falciparum ItG after 72 hrs by lactate dehydrogenase assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Antimalarial activities of 6-iodouridine and its prodrugs and potential for combination therapy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.31 | 6.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL76 | CHLOROQUINE | 4.0 | 1 | 6.70 |
| CHEMBL220442 | — | — | 1 | 5.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL76 | CHLOROQUINE | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL220442 | — | IC50 | = | 1200.0 | nM | 5.92 |