Assay Detail
Binding
CHEMBL2345478
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant full length CAMK2alpha (unknown origin) using autocamtide-2 as substrate assessed as incorporation of 32P after 30 mins by scintillation counting analysis in presence of [gamma32P]ATP relative to control
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Calcium/calmodulin-dependent protein kinase type II subunit alpha (CHEMBL4147) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Characterization of a selective CaMKII peptide inhibitor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.41 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2335444 | — | — | 1 | 7.52 |
| CHEMBL2335442 | — | — | 1 | 7.40 |
| CHEMBL2335479 | — | — | 1 | 7.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2335444 | — | IC50 | = | 30.0 | nM | 7.52 |
| CHEMBL2335442 | — | IC50 | = | 40.0 | nM | 7.40 |
| CHEMBL2335479 | — | IC50 | = | 50.0 | nM | 7.30 |