Assay Detail
Binding
CHEMBL2345818
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Displacement of SYBR from phage lambda DNA by FID assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Enterobacteria phage lambda |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
The structure of anthracycline derivatives determines their subcellular localization and cytotoxic activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.35 | 6.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL178 | DAUNORUBICIN | 4.0 | 1 | 6.85 |
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 6.14 |
| CHEMBL1117 | IDARUBICIN | 4.0 | 1 | 6.05 |
| CHEMBL2331656 | — | — | 1 | - |
| CHEMBL2022407 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL178 | DAUNORUBICIN | IC50 | = | 140.0 | nM | 6.85 |
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 730.0 | nM | 6.14 |
| CHEMBL1117 | IDARUBICIN | IC50 | = | 890.0 | nM | 6.05 |
| CHEMBL2331656 | — | IC50 | > | 40000.0 | nM | - |
| CHEMBL2022407 | — | IC50 | > | 40000.0 | nM | - |