Assay Detail
Binding
CHEMBL2353231
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of mouse APN using L-leucine-p-nitroanilide as substrate measured every 10 mins for 2 hrs by spectrophotometric analysis
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Selective aminopeptidase-N (CD13) inhibitors with relevance to cancer chemotherapy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.80 | 9.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1852660 | — | — | 1 | 9.70 |
| CHEMBL1821978 | — | — | 1 | 8.00 |
| CHEMBL1668626 | — | — | 1 | 5.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1852660 | — | Ki | = | 0.2 | nM | 9.70 |
| CHEMBL1821978 | — | Ki | = | 10.0 | nM | 8.00 |
| CHEMBL1668626 | — | Ki | = | 2000.0 | nM | 5.70 |