Assay Detail
Functional
CHEMBL2353295
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Cytotoxicity against human BGC823 cells by MTT assay
14
Total Activities
14
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | BGC-823 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and cytotoxicity evaluation of oleanolic acid derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 14 | 4.82 | 5.88 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 5.88 |
| CHEMBL168 | OLEANOLIC_ACID | — | 1 | 5.59 |
| CHEMBL2347265 | — | — | 1 | 5.38 |
| CHEMBL446073 | OLEANOLIC ACID 3-O-SUCCINATE | — | 1 | 5.25 |
| CHEMBL2347263 | — | — | 1 | 5.13 |
| CHEMBL2347260 | — | — | 1 | 5.03 |
| CHEMBL2347266 | — | — | 1 | 4.87 |
| CHEMBL2347259 | — | — | 1 | 4.79 |
| CHEMBL2347256 | — | — | 1 | 4.61 |
| CHEMBL2347261 | — | — | 1 | 4.57 |
| CHEMBL2347262 | — | — | 1 | 4.12 |
| CHEMBL2347257 | — | — | 1 | 4.09 |
| CHEMBL2347264 | — | — | 1 | 4.07 |
| CHEMBL2347258 | — | — | 1 | 4.06 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 1330.0 | nM | 5.88 |
| CHEMBL168 | OLEANOLIC_ACID | IC50 | = | 2590.0 | nM | 5.59 |
| CHEMBL2347265 | — | IC50 | = | 4180.0 | nM | 5.38 |
| CHEMBL446073 | OLEANOLIC ACID 3-O-SUCCINATE | IC50 | = | 5590.0 | nM | 5.25 |
| CHEMBL2347263 | — | IC50 | = | 7320.0 | nM | 5.13 |
| CHEMBL2347260 | — | IC50 | = | 9360.0 | nM | 5.03 |
| CHEMBL2347266 | — | IC50 | = | 13400.0 | nM | 4.87 |
| CHEMBL2347259 | — | IC50 | = | 16300.0 | nM | 4.79 |
| CHEMBL2347256 | — | IC50 | = | 24500.0 | nM | 4.61 |
| CHEMBL2347261 | — | IC50 | = | 27200.0 | nM | 4.57 |
| CHEMBL2347262 | — | IC50 | = | 76300.0 | nM | 4.12 |
| CHEMBL2347257 | — | IC50 | = | 81900.0 | nM | 4.09 |
| CHEMBL2347264 | — | IC50 | = | 84500.0 | nM | 4.07 |
| CHEMBL2347258 | — | IC50 | = | 87200.0 | nM | 4.06 |