Assay Detail
Functional
CHEMBL2353465
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Cytotoxicity against human HeLa cells assessed as growth inhibition measured after 48 hrs by XTT assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HeLa |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cytotoxicity and modulation of cancer-related signaling by (Z)- and (E)-3,4,3',5'-tetramethoxystilbene isolated from Eugenia rigida.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.21 | 5.44 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1172104 | (Z)-3,4,3',5'-TETRAMETHOXYSTILBENE | — | 1 | 5.44 |
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 5.41 |
| CHEMBL44509 | (E)-3,4,3',5'-TETRAMETHOXYSTILBENE | — | 1 | 5.10 |
| CHEMBL296411 | TRISMETHOXYRESVERATROL | — | 1 | 4.88 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1172104 | (Z)-3,4,3',5'-TETRAMETHOXYSTILBENE | IC50 | = | 3600.0 | nM | 5.44 |
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 3900.0 | nM | 5.41 |
| CHEMBL44509 | (E)-3,4,3',5'-TETRAMETHOXYSTILBENE | IC50 | = | 8000.0 | nM | 5.10 |
| CHEMBL296411 | TRISMETHOXYRESVERATROL | IC50 | = | 13300.0 | nM | 4.88 |