Assay Detail
Binding
CHEMBL2377924
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]-GR65630 from 5HT3 receptor in rat/mouse NG108 cells
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Structure-activity relationship of 5-chloro-2-methyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole analogues as 5-HT(6) receptor agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 6.11 | 6.57 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL414668 | — | — | 1 | 6.57 |
| CHEMBL1550957 | — | — | 1 | 5.64 |
| CHEMBL18785 | RU-24969 | — | 1 | - |
| CHEMBL2376491 | — | — | 1 | - |
| CHEMBL2376490 | — | — | 1 | - |
| CHEMBL2376487 | — | — | 1 | - |
| CHEMBL2376484 | — | — | 1 | - |
| CHEMBL2376483 | — | — | 1 | - |
| CHEMBL2376482 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL414668 | — | IC50 | = | 270.0 | nM | 6.57 |
| CHEMBL1550957 | — | IC50 | = | 2300.0 | nM | 5.64 |
| CHEMBL18785 | RU-24969 | IC50 | > | 1000.0 | nM | - |
| CHEMBL2376491 | — | IC50 | - | — | - | |
| CHEMBL2376490 | — | IC50 | - | — | - | |
| CHEMBL2376487 | — | IC50 | - | — | - | |
| CHEMBL2376484 | — | IC50 | - | — | - | |
| CHEMBL2376483 | — | IC50 | - | — | - | |
| CHEMBL2376482 | — | IC50 | - | — | - |