Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL2378385

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of DAAO (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

D-amino-acid oxidase (CHEMBL5485)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Structural, kinetic, and pharmacodynamic mechanisms of D-amino acid oxidase inhibition by small molecules.
Hopkins SC, Heffernan ML, Saraswat LD, Bowen CA, Melnick L, Hardy LW, Orsini MA, Allen MS, Koch P, Spear KL, Foglesong RJ, Soukri M, Chytil M, Fang QK, Jones SW, Varney MA, Panatier A, Oliet SH, Pollegioni L, Piubelli L, Molla G, Nardini M, Large TH.
J Med Chem (2013) 56 : 3710 -3724
PubMed 23631755 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.27 8.27

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL507614 1 8.27

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL507614 IC50 = 5.37 nM 8.27