Assay Detail
Binding
CHEMBL2378991
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to human 5HT7 receptor expressed in HEK-293F cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK-293F |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of aryl-biphenyl-2-ylmethylpiperazines as novel scaffolds for 5-HT(7) ligands and role of the aromatic substituents in binding to the target receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 9.22 | 9.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2164327 | — | — | 1 | 9.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2164327 | — | Ki | = | 0.6 | nM | 9.22 |