Assay Detail
Functional
CHEMBL2379101
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Antiproliferative activity against human MDA-MB-231 cells after 24 hrs by MTS assay
5
Total Activities
5
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MDA-MB-231 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Design, synthesis and antiproliferative properties of some new 5-substituted-2-iminobenzimidazole derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 7.83 | 9.55 |
| IC50 | 1 | 8.21 | 8.21 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2377273 | — | — | 1 | 9.55 |
| CHEMBL2377274 | — | — | 1 | 8.21 |
| CHEMBL2377275 | — | — | 1 | 7.77 |
| CHEMBL2377271 | — | — | 1 | 7.07 |
| CHEMBL2377272 | — | — | 1 | 6.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2377273 | — | EC50 | = | 0.28 | nM | 9.55 |
| CHEMBL2377274 | — | IC50 | = | 6.2 | nM | 8.21 |
| CHEMBL2377275 | — | EC50 | = | 17.0 | nM | 7.77 |
| CHEMBL2377271 | — | EC50 | = | 86.0 | nM | 7.07 |
| CHEMBL2377272 | — | EC50 | = | 119.0 | nM | 6.92 |