Assay Detail
Functional
CHEMBL2379285
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Antimigratory activity against human MDA-MB-231 cells after 6 hrs by Boyden chamber migration assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MDA-MB-231 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cytotoxic 3,4,5-trimethoxychalcones as mitotic arresters and cell migration inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.15 | 6.32 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL107 | COLCHICINE | 4.0 | 1 | 6.32 |
| CHEMBL285901 | — | — | 1 | 6.18 |
| CHEMBL220818 | — | — | 1 | 5.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL107 | COLCHICINE | IC50 | = | 475.0 | nM | 6.32 |
| CHEMBL285901 | — | IC50 | = | 656.0 | nM | 6.18 |
| CHEMBL220818 | — | IC50 | = | 1095.0 | nM | 5.96 |