Assay Detail
Binding
CHEMBL2379888
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Inhibition of human carbonic anhydrase-2 preincubated for 15 mins by stopped-flow CO2 hydrase assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Carbonic anhydrase inhibitors: inhibition of the β-class enzyme from the pathogenic yeast Candida glabrata with sulfonamides, sulfamates and sulfamides.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.38 | 6.56 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2376274 | — | — | 1 | 6.56 |
| CHEMBL2047796 | — | — | 1 | 6.41 |
| CHEMBL2376273 | — | — | 1 | 6.18 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2376274 | — | Ki | = | 274.0 | nM | 6.56 |
| CHEMBL2047796 | — | Ki | = | 393.0 | nM | 6.41 |
| CHEMBL2376273 | — | Ki | = | 660.0 | nM | 6.18 |