Assay Detail
Binding
CHEMBL2380136
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Inhibition of MAO-A (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
A comprehensive review on synthesis and designing aspects of coumarin derivatives as monoamine oxidase inhibitors for depression and Alzheimer's disease.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.77 | 4.86 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL24171 | BERGAPTEN | 3.0 | 1 | 4.86 |
| CHEMBL164660 | PSORALEN | 1.0 | 1 | 4.67 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL24171 | BERGAPTEN | IC50 | = | 13800.0 | nM | 4.86 |
| CHEMBL164660 | PSORALEN | IC50 | = | 21300.0 | nM | 4.67 |