Assay Detail
Binding
CHEMBL2383455
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of wild type Mycobacterium tuberculosis RNA polymerase after 10 mins by rolling circle transcription assay in presence of DNA nanocircle template NC45
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mycobacterium tuberculosis |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
X-ray crystal structures of the Escherichia coli RNA polymerase in complex with benzoxazinorifamycins.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.77 | 7.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL374478 | RIFAMPIN | 4.0 | 1 | 7.77 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL374478 | RIFAMPIN | IC50 | = | 17.0 | nM | 7.77 |