Assay Detail
Binding
CHEMBL2389280
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Inhibition of Staphylococcus aureus FabI using dodecenoyl ACP at pH 7.8
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Staphylococcus aureus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Potential of lichen secondary metabolites against Plasmodium liver stage parasites with FAS-II as the potential target.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.83 | 7.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL849 | TRICLOSAN | 4.0 | 1 | 7.60 |
| CHEMBL463212 | VULPINIC ACID | — | 1 | 4.05 |
| CHEMBL367881 | (+)-USNIC ACID | — | 1 | - |
| CHEMBL176570 | PSOROMIC ACID | — | 1 | - |
| CHEMBL1484978 | EVERNIC ACID | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL849 | TRICLOSAN | IC50 | = | 25.0 | nM | 7.60 |
| CHEMBL463212 | VULPINIC ACID | IC50 | = | 90000.0 | nM | 4.05 |
| CHEMBL367881 | (+)-USNIC ACID | IC50 | = | 190000.0 | nM | - |
| CHEMBL176570 | PSOROMIC ACID | IC50 | > | 200000.0 | nM | - |
| CHEMBL1484978 | EVERNIC ACID | IC50 | = | 170000.0 | nM | - |