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Assay Detail

CHEMBL2389291

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human KB cells after 72 hrs by Alamar Blue assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type KB
Confidence 1 — Organism
Curated By Autocuration

Target

KB (CHEMBL398)
Type CELL-LINE
Organism Homo sapiens

Publication

Potential of lichen secondary metabolites against Plasmodium liver stage parasites with FAS-II as the potential target.
Lauinger IL, Vivas L, Perozzo R, Stairiker C, Tarun A, Zloh M, Zhang X, Xu H, Tonge PJ, Franzblau SG, Pham DH, Esguerra CV, Crawford AD, Maes L, Tasdemir D.
J Nat Prod (2013) 76 : 1064 -1070
PubMed 23806111 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 4.50 4.50

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL176570 PSOROMIC ACID 1 4.50
CHEMBL1484978 EVERNIC ACID 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL176570 PSOROMIC ACID IC50 = 31600.0 nM 4.50
CHEMBL1484978 EVERNIC ACID IC50 = 190400.0 nM -