Assay Detail

CHEMBL2390264

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional

Antiplasmodial activity against sexual blood stage of Plasmodium falciparum

ChEMBL ↗

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Target

Plasmodium falciparum (CHEMBL364) ↗

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Primary target Plasmodium falciparum

CHEMBL364

Anchored from Assay target.

Protein identity Plasmodium falciparum

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Plasmodium falciparum
Confidence	1 — Organism
Curated By	Autocuration

Target

Plasmodium falciparum (CHEMBL364) ↗

Type	ORGANISM
Organism	Plasmodium falciparum

Publication

Recent advances in malaria drug discovery.

Biamonte MA, Wanner J, Le Roch KG.
Bioorg Med Chem Lett (2013) 23 : 2829 -2843
PubMed 23587422 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
EC50	1	7.44	7.44

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL416230	DECOQUINATE	2.0	1	7.44

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL416230	DECOQUINATE	EC50	=	36.0	nM	7.44