Assay Detail
Functional
CHEMBL2390440
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Antiplasmodial activity against drug-sensitive Plasmodium falciparum 3D7
6
Total Activities
6
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Recent advances in malaria drug discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 7.65 | 9.15 |
| IC50 | 1 | 8.31 | 8.31 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1082723 | CIPARGAMIN | 2.0 | 1 | 9.15 |
| CHEMBL2387268 | — | — | 1 | 8.31 |
| CHEMBL1630 | — | — | 1 | 7.96 |
| CHEMBL569864 | — | — | 1 | 7.12 |
| CHEMBL1875655 | — | — | 1 | 7.00 |
| CHEMBL588058 | — | — | 1 | 7.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1082723 | CIPARGAMIN | EC50 | = | 0.7 | nM | 9.15 |
| CHEMBL2387268 | — | IC50 | = | 4.9 | nM | 8.31 |
| CHEMBL1630 | — | EC50 | = | 11.0 | nM | 7.96 |
| CHEMBL569864 | — | EC50 | = | 75.0 | nM | 7.12 |
| CHEMBL1875655 | — | EC50 | = | 100.0 | nM | 7.00 |
| CHEMBL588058 | — | EC50 | = | 100.0 | nM | 7.00 |