Assay Detail
Binding
CHEMBL2390635
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Antagonist activity at OX2 receptor (unknown origin)
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Radiosynthesis and evaluation of [11C]EMPA as a potential PET tracer for orexin 2 receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.70 | 8.70 |
| Ki | 1 | 8.96 | 8.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2385132 | — | — | 2 | 8.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2385132 | — | Ki | = | 1.1 | nM | 8.96 |
| CHEMBL2385132 | — | IC50 | = | 2.0 | nM | 8.70 |